Bromide of Potassium in Epilepsy

Bromide of Potassium in Writer's Palsy

heard of its being given, though very likely others have tried it, and its effects were, i may say, so startling that I ask you to publish the case. I was consulted recently by an English gentleman on account of that very troublesome affection, writer's spasm, from which he had been suffering for 9 months. He was in good general health, but the spasm of his right hand was so bad whenever be hel...

Potassium Channelopathies of Epilepsy

Channelopathies are inherited genetic changes in ion channel genes that generate a disease. Given the pivotal role of voltage-dependent potassium channels in moderating neuronal excitability, it is not surprising that these channels are well represented among the channelopathies contributing to epilepsy. Voltage-dependent potassium channels are regarded as the “initial responders” that shape an...

Sir Charles Locock and potassium bromide.

On 12 May 1857, Edward Sieveking read a paper on epilepsy to the Royal Medical and Chirurgical Society in London. During the discussion that followed Sir Charles Locock, obstetrician to Queen Victoria, was reported to have commented that during the past 14 months he had used potassium bromide to successfully stop epileptic seizures in all but one of 14 or 15 women with 'hysterical' or catamenia...

Rare Gas Mobility in Pure and Doped Potassium Bromide

The mobility of the inert gases argon and xenon in pure and doped single crystals of KBr was studied. The gases were introduced by ion bombardment. The recently established system of stages was used to interpret the results. Normal volume diffusion was found for xenon at low gas concentration, the activation enthalpy being 1.4 + 0.2 eV. This release was independent of doping, thus favoring a tr...

Bromide of Potassium as an Antidote to Chloroform